Basic Information:

Symbol	OSBPL9
Synonyms	ORP9; OSBP4
Protein Name	Oxysterol-binding protein-related protein 9 (ORP-9) (OSBP-related protein 9)
Species	Human
Entrez ID	114883
Uniprot ID	Q96SU4
Membrane Contact Site	ER-Endosome; Endosome-ER
Location (from literature)	Endosome
Cell line/Tissue	HeLa cells; HEK293T cells; COS-7 cells
Experimental Method	Low throughput experimental methods
Protein Sequence
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Complex Information:

Complex ID	Subunit of complex	Subcellular location	Species	More
CMCS00167	OSBPL10; OSBPL9; VAPA; VAPB; PI(4)P	ER-Endosome; Endosome-ER	Human	more

Expression Overview of OSBPL9:

Homology Information of OSBPL9:

Uniprot ID	Q96SU4
EggNOG	KOG2210
HOGENOM	CLU_012334_3_0_1
OrthoDB	1018068at2759
TreeFam	TF312807
GeneTree	ENSGT00940000154690

References:

Pubmed ID	34817532
DOI	10.1083/jcb.202103141
Description	ORP10 localizes in a PI4P-dependent manner at ER–endosome membrane contact sites tethered by ORP9 and VAP, where it mediates countertransport of PI4P and PS.
Description of experimental evidence	The protein was validated by immunofluorescence microscopy, live-cell imaging, image analysis, coimmunoprecipitation and LC-MS/MS in HeLa cells, HEK293T cells and COS-7 cells.
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