Detail Information
P450 Protein:
| P450 Symbol | CYP71D495 |
| Protein Name | Casbene 9-oxidase |
| Uniprot ID | A0A191VYX7 |
| Species | Jatropha curcas (Barbados nut) |
| Txid | 180498 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H32 → C20H32O |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP71D495
Substrate Information:
| Substrate Name | Casbene |
| Substrate Chemical Formula | C20H32 |
| Substrate PubChem CID | 5280437 |
| Substrate Smiles | C/C1=CCC/C(C)=C/[C@@H]2[C@H](CC/C(C)=C/CC1)C2(C)C |
| Substrate Structure |
Product Information:
| Product Name | 9-Hydroxycasbene |
| Product Chemical Formula | C20H32O |
| Product Smiles | C1/C(/C)=C/[C@]2([C@@](C)(C)[C@@]2([H])CC/C(/C)=C/CC(O)/C(/C)=C/C1)[H] |
| Product Structure |
References:
| Title: | A Cytochrome P450-Mediated Intramolecular Carbon-Carbon Ring Closure in the Biosynthesis of Multidrug-Resistance-Reversing Lathyrane Diterpenoids. |
| PMID: | 27272333 |
| Journal: | Chembiochem : a European journal of chemical biology |
| Year: | 2016/9/2 |