Detail Information
P450 Protein:
| P450 Symbol | CYP71AN24 |
| Protein Name | Phenylacetaldehyde oxime monooxygenase CYP71AN24 |
| Uniprot ID | A0A068Q609 |
| EC Number | 1.14.14.44; 1.14.14.77 |
| Gene ID | 103337951 |
| Species | Prunus mume (Japanese apricot) (Armeniaca mume) |
| Txid | 102107 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C8H7N + C17H21N4O9P-2 + O2 → C8H7NO + C17H18N4O9P-3 + H2O + H+ |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
| RheaID | 52164 |
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CYP71AN24
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Substrate Information:
| Substrate Name | Phenylacetonitrile |
| Substrate Chemical Formula | C8H7N |
| Substrate PubChem CID | 8794 |
| Substrate Smiles | C1=CC=C(C=C1)CC#N |
| Substrate Structure |
| Substrate Name | FMNH2 |
| Substrate Chemical Formula | C17H21N4O9P-2 |
| Substrate PubChem CID | 44229161 |
| Substrate Smiles | CC1=CC2=C(C=C1C)N(C3=C(N2)C(=O)NC(=O)N3)C[C@@H]([C@@H]([C@@H](COP(=O)([O-])[O-])O)O)O |
| Substrate Structure |
| Substrate Name | O2 |
| Substrate Chemical Formula | O2 |
| Substrate PubChem CID | 977 |
| Substrate CAS Number | 7782-44-7 |
| Substrate Smiles | O=O |
| Substrate Structure |
Product Information:
| Product Name | (R)-Mandelonitrile |
| Product Chemical Formula | C8H7NO |
| Product PubChem CID | 9548674 |
| Product Smiles | C1=CC=C(C=C1)[C@H](C#N)O |
| Product Structure |
| Product Name | FMN |
| Product Chemical Formula | C17H18N4O9P-3 |
| Product PubChem CID | 44229199 |
| Product Smiles | CC1=CC2=C(C=C1C)N(C3=NC(=NC(=O)C3=N2)[O-])C[C@@H]([C@@H]([C@@H](COP(=O)([O-])[O-])O)O)O |
| Product Structure |
| Product Name | H2O |
| Product Chemical Formula | H2O |
| Product PubChem CID | 962 |
| Product CAS Number | 7732-18-5 |
| Product Smiles | O |
| Product Structure |
| Product Name | H+ |
| Product Chemical Formula | H+ |
| Product PubChem CID | 1038 |
| Product CAS Number | 12408-02-5 |
| Product Smiles | [H+] |
| Product Structure |
References:
| Title: | Identification and characterization of CYP79D16 and CYP71AN24 catalyzing the first and second steps in L-phenylalanine-derived cyanogenic glycoside biosynthesis in the Japanese apricot, Prunus mume Sieb. et Zucc. |
| PMID: | 25015725 |
| Journal: | Plant molecular biology |
| Year: | 2014/9/1 |