Detail Information
P450 Protein:
| P450 Symbol | CYP720B12 |
| Protein Name | CYP720B12 |
| Uniprot ID | A0A076U5L5 |
| Species | Pinus contorta (Shore pine) (Lodgepole pine) |
| Txid | 3339 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H34O → C20H32O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP720B12
Substrate Information:
| Substrate Name | 13-Hydroxyl-8(14)-Abietene |
| Substrate Chemical Formula | C20H34O |
| Substrate PubChem CID | 71571618 |
| Substrate Smiles | C1C[C@@](C)2[C@H]3CCC(O)(C(C)C)C=C3CCC2[C@@](C)(C)C1 |
| Substrate Structure |
Product Information:
| Product Name | 13-Hydroxyl-8(14)-Abietic Acid |
| Product Chemical Formula | C20H32O3 |
| Product Smiles | C1C[C@@](C)2[C@H]3CCC(C(C)C)(O)C=C3CCC2[C@@](C(O)=O)(C)C1 |
| Product Structure |
References:
| Title: | Modularity of Conifer Diterpene Resin Acid Biosynthesis: P450 Enzymes of Different CYP720B Clades Use Alternative Substrates and Converge on the Same Products. |
| PMID: | 26936895 |
| Journal: | Plant physiology |
| Year: | 2016/5/1 |