Detail Information
P450 Protein:
| P450 Symbol | TleB |
| Protein Name | Cytochrome P-450 |
| Uniprot ID | A0A077KEB8 |
| Species | Streptomyces blastmyceticus |
| Txid | 68180 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C17H25N3O2 → C17H23N3O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3;CH |
TleB
Substrate Information:
| Substrate Name | NMVT |
| Substrate Chemical Formula | C17H25N3O2 |
| Substrate PubChem CID | 91115345 |
| Substrate Smiles | CC(C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)CO)NC |
| Substrate Structure |
Product Information:
| Product Name | Indolactam V |
| Product Chemical Formula | C17H23N3O2 |
| Product PubChem CID | 105000 |
| Product Smiles | CC(C)[C@H]1C(=O)N[C@@H](CC2=CNC3=C2C(=CC=C3)N1C)CO |
| Product Structure |
References:
| Title: | Enzymatic Formation of Indolactam Scaffold by C-N Bond-Forming Cytochrome P450 Oxidases in Teleocidin Biosynthesis. |
| PMID: | 32996659 |
| Journal: | Chemistry (Weinheim an der Bergstrasse, Germany) |
| Year: | 2021/2/10 |