Detail Information
P450 Protein:
| P450 Symbol | CYP716A14v2 |
| Protein Name | CYP716A14v2 |
| Uniprot ID | A0A0B4L1W4 |
| Species | Artemisia annua (Sweet wormwood) |
| Txid | 35608 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O → C30H48O |
| Reaction Type | Oxidation |
| Chemical Bond | CH-OH |
CYP716A14v2
Substrate Information:
| Substrate Name | Lupeol |
| Substrate Chemical Formula | C30H50O |
| Substrate PubChem CID | 259846 |
| Substrate Smiles | CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C |
| Substrate Structure |
Product Information:
| Product Name | Lupenone |
| Product Chemical Formula | C30H48O |
| Product PubChem CID | 92158 |
| Product Smiles | CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CCC(=O)C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)C)C |
| Product Structure |
References:
| Title: | OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua. |
| PMID: | 25576188 |
| Journal: | The Plant cell |
| Year: | 2015/1/1 |