Detail Information

P450 Protein:

P450 SymbolCYP716A14v2
Protein NameCYP716A14v2
Uniprot IDA0A0B4L1W4
SpeciesArtemisia annua (Sweet wormwood)
Txid 35608
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
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Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O → C30H48O
Reaction TypeOxidation
Chemical BondCH-OH

Beta-Amyrin

CYP716A14v2

Beta-Amyrone

Substrate Information:

Substrate Name Beta-Amyrin
Substrate Chemical FormulaC30H50O
Substrate PubChem CID73145
Substrate SmilesC[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C
Substrate Structure

Product Information:

Product Name Beta-Amyrone
Product Chemical FormulaC30H48O
Product PubChem CID12306160
Product SmilesC[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CCC(=O)C5(C)C)C)C)[C@@H]1CC(CC2)(C)C)C
Product Structure

References:

Title: OSC2 and CYP716A14v2 catalyze the biosynthesis of triterpenoids for the cuticle of aerial organs of Artemisia annua.
PMID: 25576188
Journal: The Plant cell
Year: 2015/1/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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