Detail Information
P450 Protein:
| P450 Symbol | CYP90B27 |
| Protein Name | CYP90B27v1 |
| Uniprot ID | A0A0F6PML0 |
| Species | Veratrum californicum |
| Txid | 50242 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C27H46O → C27H46O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP90B27
Substrate Information:
| Substrate Name | Cholesterol |
| Substrate Chemical Formula | C27H46O |
| Substrate PubChem CID | 5997 |
| Substrate Smiles | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| Substrate Structure |
Product Information:
| Product Name | 22R-Hydroxycholesterol |
| Product Chemical Formula | C27H46O2 |
| Product PubChem CID | 167685 |
| Product Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)[C@@H](CCC(C)C)O |
| Product Structure |
References:
| Title: | Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. |
| PMID: | 25939370 |
| Journal: | The Plant journal : for cell and molecular biology |
| Year: | 2015/6/1 |