Detail Information

P450 Protein:

P450 SymbolCYP90G1
Protein NameCYP90G1v3
Uniprot IDA0A0F6PMN4
SpeciesVeratrum californicum
Txid 50242
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular LocationMitochondrion inner membrane; Peripheral membrane protein
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C27H46O3 → C27H44O3
Reaction TypeOxidation
Chemical BondCH-OH

22(R),26-Dihydroxycholesterol

CYP90G1

22-Keto-26-Hydroxycholesterol

Substrate Information:

Substrate Name 22(R),26-Dihydroxycholesterol
Substrate Chemical FormulaC27H46O3
Substrate PubChem CID122706556
Substrate SmilesC[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)[C@@H](CCC(C)CO)O
Substrate Structure

Product Information:

Product Name 22-Keto-26-Hydroxycholesterol
Product Chemical FormulaC27H44O3
Product PubChem CID189988
Product SmilesC[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C(=O)CCC(C)CO
Product Structure

References:

Title: Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells.
PMID: 25939370
Journal: The Plant journal : for cell and molecular biology
Year: 2015/6/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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