Detail Information
P450 Protein:
| P450 Symbol | CYP90G1 |
| Protein Name | CYP90G1v3 |
| Uniprot ID | A0A0F6PMN4 |
| Species | Veratrum californicum |
| Txid | 50242 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C27H47NO2 → C27H45NO2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH-OH |
CYP90G1
Substrate Information:
| Substrate Name | 22-Hydroxy-26-Aminocholesterol |
| Substrate Chemical Formula | C27H47NO2 |
| Substrate Smiles | C1C[C@@](C)2[C@]([H])3CC[C@@](C)4C([C@@H]([C@H](O)CCC(CN)C)C)CCC4[C@]3([H])CC=C2C[C@H]1O |
| Substrate Structure |
Product Information:
| Product Name | 22-Keto-26-Aminocholesterol |
| Product Chemical Formula | C27H45NO2 |
| Product Smiles | C1C[C@@](C)2[C@]([H])3CC[C@@](C)4C([C@H](C)C(=O)CCC(CN)C)CCC4[C@]3([H])CC=C2C[C@H]1O |
| Product Structure |
References:
| Title: | Elucidating steroid alkaloid biosynthesis in Veratrum californicum: production of verazine in Sf9 cells. |
| PMID: | 25939370 |
| Journal: | The Plant journal : for cell and molecular biology |
| Year: | 2015/6/1 |