Detail Information
P450 Protein:
| P450 Symbol | CYP750B1 |
| Protein Name | (+)-sabinene-3-hydroxylase |
| Uniprot ID | A0A0F7KN88 |
| Species | Thuja plicata (Western red-cedar) (Giant arborvitae) |
| Txid | 3316 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H16 → C10H16O |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP750B1
Substrate Information:
| Substrate Name | (+)-Sabinene |
| Substrate Chemical Formula | C10H16 |
| Substrate PubChem CID | 10887971 |
| Substrate Smiles | CC(C)[C@]12CCC(=C)[C@H]1C2 |
| Substrate Structure |
Product Information:
| Product Name | Trans-Sabin-3-Ol |
| Product Chemical Formula | C10H16O |
| Product PubChem CID | 94147 |
| Product Smiles | [C@@]([C@H](C)C)12C[C@@H]1C(=C)[C@H](O)C2 |
| Product Structure |
References:
| Title: | The gymnosperm cytochrome P450 CYP750B1 catalyzes stereospecific monoterpene hydroxylation of (+)-sabinene in thujone biosynthesis in western redcedar. |
| PMID: | 25829465 |
| Journal: | Plant physiology |
| Year: | 2015/5/1 |