Detail Information
P450 Protein:
| P450 Symbol | CYP716A253 |
| Protein Name | Cytochrome P450 |
| Uniprot ID | A0A161ABB0 |
| Species | Ocimum basilicum (Sweet basil) |
| Txid | 39350 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O2 → C30H48O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2-OH |
CYP716A253
Substrate Information:
| Substrate Name | Uvaol |
| Substrate Chemical Formula | C30H50O2 |
| Substrate PubChem CID | 92802 |
| Substrate Smiles | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)CO |
| Substrate Structure |
Product Information:
| Product Name | Ursolic Acid |
| Product Chemical Formula | C30H48O3 |
| Product PubChem CID | 64945 |
| Product Smiles | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O |
| Product Structure |
References:
| Title: | Two CYP716A subfamily cytochrome P450 monooxygenases of sweet basil play similar but nonredundant roles in ursane- and oleanane-type pentacyclic triterpene biosynthesis. |
| PMID: | 28967669 |
| Journal: | The New phytologist |
| Year: | 2017/4/1 |