Detail Information

P450 Protein:

P450 SymbolCYP72A208
Protein NameSteroid C-26 oxygenase
Uniprot IDA0A193PE91
SpeciesSolanum tuberosum (Potato)
Txid 4113
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C27H46O → C26H44O3
Reaction TypeOxidation
Chemical BondCH3

Cholesterol

CYP72A208

16Alpha,22,26-Trihydroxycholesterol

Substrate Information:

Substrate Name Cholesterol
Substrate Chemical FormulaC27H46O
Substrate PubChem CID5997
Substrate SmilesC[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C
Substrate Structure

Product Information:

Product Name 16Alpha,22,26-Trihydroxycholesterol
Product Chemical FormulaC26H44O3
Product SmilesC1C[C@@](C)2[C@]([H])3CC[C@@](C)4[C@@H]([C@@H](C(O)CC[C@@]([H])(CO)C)C)[C@H](O)C[C@@]4([H])[C@]3([H])CC=C2C[C@H]1O
Product Structure

References:

Title: Characterization of C-26 aminotransferase, indispensable for steroidal glycoalkaloid biosynthesis.
PMID: 34273198
Journal: The Plant journal : for cell and molecular biology
Year: 2021/10/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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