Detail Information
P450 Protein:
| P450 Symbol | CYP716E41 |
| Protein Name | Oleanolic acid 6-beta-oxidase |
| Uniprot ID | A0A1I9Q5Y6 |
| Species | Centella asiatica |
| Txid | 48106 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H48O3 → C30H48O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP716E41
Substrate Information:
| Substrate Name | Ursolic Acid |
| Substrate Chemical Formula | C30H48O3 |
| Substrate PubChem CID | 64945 |
| Substrate Smiles | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C(=O)O |
| Substrate Structure |
Product Information:
| Product Name | 6Beta-Hydroxy-Ursolic Acid |
| Product Chemical Formula | C30H48O4 |
| Product PubChem CID | 20055642 |
| Product Smiles | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(C[C@H]([C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)O)C)[C@@H]2[C@H]1C)C)C(=O)O |
| Product Structure |
References:
| Title: | The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis. |
| PMID: | 28165039 |
| Journal: | Nature communications |
| Year: | 2017/2/6 |