Detail Information

P450 Protein:

P450 SymbolCYP716E41
Protein NameOleanolic acid 6-beta-oxidase
Uniprot IDA0A1I9Q5Y6
SpeciesCentella asiatica
Txid 48106
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H48O4 → C30H48O5
Reaction TypeOxidation
Chemical BondCH3

Maslinic Acid

CYP716E41

6Beta-Hydroxymaslinic Acid

Substrate Information:

Substrate Name Maslinic Acid
Substrate Chemical FormulaC30H48O4
Substrate PubChem CID73659
Substrate SmilesC[C@@]12CC[C@@H]3[C@@]([C@H]1CC=C4[C@]2(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)(C[C@H]([C@@H](C3(C)C)O)O)C
Substrate Structure

Product Information:

Product Name 6Beta-Hydroxymaslinic Acid
Product Chemical FormulaC30H48O5
Product Smiles[C@H](O)1C[C@@](C)2C3CC=C4C5C[C@@](C)(C)CC[C@]5(C(O)=O)CC[C@@]4(C)[C@]3(C)C[C@@H](O)C2[C@@](C)(C)[C@H]1O
Product Structure

References:

Title: The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis.
PMID: 28165039
Journal: Nature communications
Year: 2017/2/6

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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