Detail Information

P450 Protein:

P450 SymbolCYP716C11
Protein NameOleanolic acid 2-alpha-oxidase
Uniprot IDA0A1I9Q5Y7
SpeciesCentella asiatica
Txid 48106
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H48O4 → C30H48O5
Reaction TypeOxidation
Chemical BondCH3

6Beta-Hydroxy-Oleanolic Acid

CYP716C11

6Beta-Hydroxymaslinic Acid

Substrate Information:

Substrate Name 6Beta-Hydroxy-Oleanolic Acid
Substrate Chemical FormulaC30H48O4
Substrate PubChem CID12443148
Substrate SmilesC[C@]12CC[C@@H](C([C@@H]1[C@@H](C[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)O)(C)C)O
Substrate Structure

Product Information:

Product Name 6Beta-Hydroxymaslinic Acid
Product Chemical FormulaC30H48O5
Product Smiles[C@H](O)1C[C@@](C)2C3CC=C4C5C[C@@](C)(C)CC[C@]5(C(O)=O)CC[C@@]4(C)[C@]3(C)C[C@@H](O)C2[C@@](C)(C)[C@H]1O
Product Structure

References:

Title: The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis.
PMID: 28165039
Journal: Nature communications
Year: 2017/2/6

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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