Detail Information
P450 Protein:
| P450 Symbol | CYP716S5 |
| Protein Name | Beta-amyrin 12,13-epoxidase |
| Uniprot ID | A0A1I9Q5Z1 |
| Species | Platycodon grandiflorus (Balloon flower) (Campanula grandiflora) |
| Txid | 94286 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H48O3 → C30H48O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP716S5
Substrate Information:
| Substrate Name | Oleanolic Acid |
| Substrate Chemical Formula | C30H48O3 |
| Substrate PubChem CID | 10494 |
| Substrate Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | 12,13Alpha-Epoxyoleanolic Acid |
| Product Chemical Formula | C30H48O4 |
| Product Smiles | C1C[C@@](C)2C3C[C@@H]4O[C@@]44C5C[C@](C)(C)CC[C@]5(C(O)=O)CC[C@@]4(C)[C@]3(C)CCC2[C@@](C)(C)[C@H]1O |
| Product Structure |
References:
| Title: | The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis. |
| PMID: | 28165039 |
| Journal: | Nature communications |
| Year: | 2017/2/6 |