Detail Information

P450 Protein:

P450 SymbolCYP716A179
Protein NameCytochrome P450 716A179
Uniprot IDA0A1L7NXK5
SpeciesGlycyrrhiza uralensis (Chinese licorice) (Glycyrrhiza shiheziensis)
Txid 74613
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O → C30H50O2
Reaction TypeOxidation
Chemical BondCH3

Beta-Amyrin

CYP716A179

Erythrodiol

Substrate Information:

Substrate Name Beta-Amyrin
Substrate Chemical FormulaC30H50O
Substrate PubChem CID73145
Substrate SmilesC[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C
Substrate Structure

Product Information:

Product Name Erythrodiol
Product Chemical FormulaC30H50O2
Product PubChem CID101761
Product SmilesC[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)CO)C)C)(C)C)O
Product Structure

References:

Title: CYP716A179 functions as a triterpene C-28 oxidase in tissue-cultured stolons of Glycyrrhiza uralensis.
PMID: 28008473
Journal: Plant cell reports
Year: 2017/3/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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