Detail Information

P450 Protein:

P450 SymbolHinD
Protein NameNocardicin N-oxygenase
Uniprot IDA0A1M4Y7D5
SpeciesStreptoalloteichus hindustanus
Txid 2017
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C17H25N3O2 → C17H23N3O2
Reaction TypeOxidation
Chemical BondCH3;CH

NMVT

HinD

Indolactam V

Substrate Information:

Substrate Name NMVT
Substrate Chemical FormulaC17H25N3O2
Substrate PubChem CID91115345
Substrate SmilesCC(C)[C@@H](C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)CO)NC
Substrate Structure

Product Information:

Product Name Indolactam V
Product Chemical FormulaC17H23N3O2
Product PubChem CID105000
Product SmilesCC(C)[C@H]1C(=O)N[C@@H](CC2=CNC3=C2C(=CC=C3)N1C)CO
Product Structure

References:

Title: Enzymatic Formation of Indolactam Scaffold by C-N Bond-Forming Cytochrome P450 Oxidases in Teleocidin Biosynthesis.
PMID: 32996659
Journal: Chemistry (Weinheim an der Bergstrasse, Germany)
Year: 2021/2/10

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics