Detail Information
P450 Protein:
| P450 Symbol | CYP82P2 |
| Protein Name | Dihydrosanguinarine 10-hydroxylase |
| Uniprot ID | A0A2Z6BXW3 |
| Species | Eschscholzia californica subsp. californica |
| Txid | 222997 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H15NO4 → C20H15NO5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP82P2
Substrate Information:
| Substrate Name | Dihydrosanguinarine |
| Substrate Chemical Formula | C20H15NO4 |
| Substrate PubChem CID | 124069 |
| Substrate Smiles | CN1CC2=C(C=CC3=C2OCO3)C4=C1C5=CC6=C(C=C5C=C4)OCO6 |
| Substrate Structure |
Product Information:
| Product Name | 10-Hydroxydihydrosanguinarine |
| Product Chemical Formula | C20H15NO5 |
| Product PubChem CID | 440596 |
| Product Smiles | CN1CC2=C(C3=C1C4=CC5=C(C=C4C=C3)OCO5)C(=CC6=C2OCO6)O |
| Product Structure |
References:
| Title: | Mining of the Uncharacterized Cytochrome P450 Genes Involved in Alkaloid Biosynthesis in California Poppy Using a Draft Genome Sequence. |
| PMID: | 29301019 |
| Journal: | Plant & cell physiology |
| Year: | 2018/2/1 |