Detail Information
P450 Protein:
| P450 Symbol | CYP716E26 |
| Protein Name | Beta-amyrin 6-beta-monooxygenase |
| Uniprot ID | A0A3Q7HS74 |
| EC Number | 1.14.14.64 |
| Gene ID | 101250025 |
| Species | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
| Txid | 4081 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O → C30H50O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP716E26
Substrate Information:
| Substrate Name | Alpha-Amyrin |
| Substrate Chemical Formula | C30H50O |
| Substrate PubChem CID | 73170 |
| Substrate Smiles | C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)C |
| Substrate Structure |
Product Information:
| Product Name | 6Beta-Hydroxy-Alpha-Amyrin |
| Product Chemical Formula | C30H50O2 |
| Product Smiles | C1C[C@@](C)2C3CC=C4C5[C@@H](C)[C@H](C)CC[C@]5(C)CC[C@@]4(C)[C@]3(C)C[C@@H](O)C2[C@@](C)(C)[C@H]1O |
| Product Structure |
References:
| Title: | Functional Characterization of CYP716 Family P450 Enzymes in Triterpenoid Biosynthesis in Tomato. |
| PMID: | 28194155 |
| Journal: | Frontiers in plant science |
| Year: | 2017/1/1 |