Detail Information
P450 Protein:
| P450 Symbol | CYP72A610 |
| Protein Name | CYP72A610 |
| Uniprot ID | A0A4Y5UJ78 |
| Species | Camptotheca acuminata (Happy tree) |
| Txid | 16922 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C10H14O4 → C16H24O10 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2;OH |
CYP72A610
Substrate Information:
| Substrate Name | 7-Deoxyloganetic Acid |
| Substrate Chemical Formula | C10H14O4 |
| Substrate PubChem CID | 25203533 |
| Substrate Smiles | C[C@H]1CC[C@H]2[C@@H]1[C@@H](OC=C2C(=O)O)O |
| Substrate Structure |
Product Information:
| Product Name | Loganic Acid |
| Product Chemical Formula | C16H24O10 |
| Product PubChem CID | 89640 |
| Product Smiles | C[C@H]1[C@H](C[C@H]2[C@@H]1[C@@H](OC=C2C(=O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)O |
| Product Structure |
References:
| Title: | Bifunctional Cytochrome P450 Enzymes Involved in Camptothecin Biosynthesis. |
| PMID: | 31117393 |
| Journal: | ACS chemical biology |
| Year: | 2019/6/21 |