Detail Information
P450 Protein:
| P450 Symbol | CYP716A155 |
| Protein Name | CYP01 |
| Uniprot ID | A0A6G7GG58 |
| Species | Rosmarinus officinalis (Rosemary) (Salvia rosmarinus) |
| Txid | 39367 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O → C30H48O3 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP716A155
Substrate Information:
| Substrate Name | Beta-Amyrin |
| Substrate Chemical Formula | C30H50O |
| Substrate PubChem CID | 73145 |
| Substrate Smiles | C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C |
| Substrate Structure |
Product Information:
| Product Name | OLEANOLIC ACID |
| Product Chemical Formula | C30H48O3 |
| Product PubChem CID | 10494 |
| Product Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O |
| Product Structure |
References:
| Title: | Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid. |
| PMID: | 31309269 |
| Journal: | Applied microbiology and biotechnology |
| Year: | 2019/9/1 |