Detail Information

P450 Protein:

P450 SymbolCYP51H10
Protein NameCytochrome P450 CYP51H10
Uniprot IDA1BQV1
SpeciesAvena strigosa (black oat)
Txid 38783
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular LocationMembrane; Single-pass membrane protein
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O2 → C30H50O3
Reaction TypeOxidation
Chemical BondC-CH;CH2;CH3

Maniladiol

CYP51H10

12,13Beta-Epoxy-16Beta-Hydroxy-Beta-Amyrin

Substrate Information:

Substrate Name Maniladiol
Substrate Chemical FormulaC30H50O2
Substrate PubChem CID397934
Substrate SmilesC[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@@H]([C@@]5([C@H]4CC(CC5)(C)C)C)O)C)C)(C)C)O
Substrate Structure

Product Information:

Product Name 12,13Beta-Epoxy-16Beta-Hydroxy-Beta-Amyrin
Product Chemical FormulaC30H50O3
Product PubChem CID90658344
Product SmilesC1C[C@@](C)2[C@]([H])3C[C@H]4O[C@]44[C@@]([H])5C[C@](C)(C)CC[C@]5(C)[C@@H](O)C[C@@]4(C)[C@]3(C)CC[C@@]2([H])[C@@](C)(C)[C@H]1O
Product Structure

References:

Title: Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants.
PMID: 23940321
Journal: Proceedings of the National Academy of Sciences of the United States of America
Year: 2013/8/27

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics