Detail Information
P450 Protein:
| P450 Symbol | CYP264B1 |
| Protein Name | (+)-eremophilene synthase |
| Uniprot ID | A9FZ87 |
| EC Number | 4.2.3.164 |
| Species | Sorangium cellulosum (strain So ce56) (Polyangium cellulosum (strain So ce56)) |
| Txid | 448385 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H28O7P2 → C15H24 + HO7P2-3 |
| Reaction Type | Decomposition |
| Chemical Bond | C-O |
| RheaID | 52804 |
CYP264B1
+
Substrate Information:
| Substrate Name | (2E,6E)-Farnesyl Diphosphate |
| Substrate Chemical Formula | C15H28O7P2 |
| Substrate PubChem CID | 445713 |
| Substrate Smiles | CC(=CCC/C(=C/CC/C(=C/COP(=O)(O)OP(=O)(O)O)/C)/C)C |
| Substrate Structure |
Product Information:
| Product Name | (+)-Eremophilene |
| Product Chemical Formula | C15H24 |
| Product PubChem CID | 6431897 |
| Product Smiles | C[C@@H]1CCC=C2[C@]1(C[C@H](CC2)C(=C)C)C |
| Product Structure |
| Product Name | Diphosphate |
| Product Chemical Formula | HO7P2-3 |
| Product PubChem CID | 4097574 |
| Product Smiles | OP(=O)([O-])OP(=O)([O-])[O-] |
| Product Structure |
References:
| Title: | Complete genome sequence of the myxobacterium Sorangium cellulosum. |
| PMID: | 17965706 |
| Journal: | Nature biotechnology |
| Year: | 2007/11/1 |
| Title: | Characterization of the gene cluster CYP264B1-geoA from Sorangium cellulosum So ce56: biosynthesis of (+)-eremophilene and its hydroxylation. |
| PMID: | 25504914 |
| Journal: | Chembiochem : a European journal of chemical biology |
| Year: | 2015/1/19 |