Detail Information
P450 Protein:
| P450 Symbol | CYP124A1 |
| Protein Name | Cytochrome P450 124A1, Cyp124A1 |
| Uniprot ID | B2HHT9 |
| Gene ID | 64262033 |
| Species | Mycobacterium marinum (strain ATCC BAA-535 / M) |
| Txid | 216594 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C27H46O → C27H46O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP124A1
Substrate Information:
| Substrate Name | Cholesterol |
| Substrate Chemical Formula | C27H46O |
| Substrate PubChem CID | 5997 |
| Substrate Smiles | C[C@H](CCCC(C)C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C |
| Substrate Structure |
Product Information:
| Product Name | 27-Hydroxycholesterol |
| Product Chemical Formula | C27H46O2 |
| Product PubChem CID | 123976 |
| Product Smiles | C[C@H](CCC[C@@H](C)[C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)CO |
| Product Structure |
References:
| Title: | Linking cytochrome P450 enzymes from Mycobacterium tuberculosis to their cognate ferredoxin partners. |
| PMID: | 30136203 |
| Journal: | Applied microbiology and biotechnology |
| Year: | 2018/11/1 |