Detail Information
P450 Protein:
| P450 Symbol | CYP720B4 |
| Protein Name | CYP720B4 |
| Uniprot ID | E5FA70 |
| Species | Picea sitchensis (Sitka spruce) (Pinus sitchensis) |
| Txid | 3332 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H32 → C20H30O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP720B4
Substrate Information:
| Substrate Name | Isopimaradiene |
| Substrate Chemical Formula | C20H32 |
| Substrate PubChem CID | 13969536 |
| Substrate Smiles | C[C@@]1(CC[C@H]2C(=CC[C@@H]3[C@@]2(CCCC3(C)C)C)C1)C=C |
| Substrate Structure |
Product Information:
| Product Name | Isopimaric Acid |
| Product Chemical Formula | C20H30O2 |
| Product PubChem CID | 442048 |
| Product Smiles | C[C@@]1(CC[C@H]2C(=CC[C@@H]3[C@@]2(CCC[C@@]3(C)C(=O)O)C)C1)C=C |
| Product Structure |
References:
| Title: | Modularity of Conifer Diterpene Resin Acid Biosynthesis: P450 Enzymes of Different CYP720B Clades Use Alternative Substrates and Converge on the Same Products. |
| PMID: | 26936895 |
| Journal: | Plant physiology |
| Year: | 2016/5/1 |