Detail Information
P450 Protein:
| P450 Symbol | PcCYP_65a |
| Protein Name | Cytochrome P450 |
| Uniprot ID | G5EJU5 |
| Species | Phanerodontia chrysosporium (White-rot fungus) (Sporotrichum pruinosum) |
| Txid | 2822231 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H12O5 → C15H12O6 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
PcCYP_65a
Substrate Information:
| Substrate Name | Naringenin |
| Substrate Chemical Formula | C15H12O5 |
| Substrate PubChem CID | 932 |
| Substrate Smiles | C(O)1C=C2OC(C3C=CC(O)=CC=3)CC(=O)C2=C(O)C=1 |
| Substrate Structure |
Product Information:
| Product Name | ERIODICTYOL |
| Product Chemical Formula | C15H12O6 |
| Product PubChem CID | 440735 |
| Product Smiles | C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC(=C(C=C3)O)O |
| Product Structure |
References:
| Title: | Enzymatic properties of cytochrome P450 catalyzing 3'-hydroxylation of naringenin from the white-rot fungus Phanerochaete chrysosporium. |
| PMID: | 19576179 |
| Journal: | Biochemical and biophysical research communications |
| Year: | 2009/9/11 |