Detail Information
P450 Protein:
| P450 Symbol | CYP72A63 |
| Protein Name | 11-oxo-beta-amyrin 30-oxidase |
| Uniprot ID | H1A981 |
| EC Number | 1.14.14.115 |
| Species | Medicago truncatula (Barrel medic) (Medicago tribuloides) |
| Txid | 3880 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O → C30H50O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP72A63
Substrate Information:
| Substrate Name | Beta-Amyrin |
| Substrate Chemical Formula | C30H50O |
| Substrate PubChem CID | 73145 |
| Substrate Smiles | C[C@@]12CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]1CC(CC2)(C)C)C |
| Substrate Structure |
Product Information:
| Product Name | 30-Hydroxy-Beta-Amyrin |
| Product Chemical Formula | C30H50O2 |
| Product PubChem CID | 12801541 |
| Product Smiles | C[C@]12CC[C@](C[C@H]1C3=CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)(C)CO |
| Product Structure |
References:
| Title: | Triterpene functional genomics in licorice for identification of CYP72A154 involved in the biosynthesis of glycyrrhizin. |
| PMID: | 22128119 |
| Journal: | The Plant cell |
| Year: | 2011/11/1 |