Detail Information
P450 Protein:
| P450 Symbol | CYP716A154 |
| Protein Name | Cytochrome P450 |
| Uniprot ID | I1TEM3 |
| Species | Catharanthus roseus (Madagascar periwinkle) (Vinca rosea) |
| Txid | 4058 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O2 → C30H47O3- |
| Reaction Type | Oxidation |
| Chemical Bond | CH-OH |
CYP716A154
Substrate Information:
| Substrate Name | Betulin |
| Substrate Chemical Formula | C30H50O2 |
| Substrate PubChem CID | 72326 |
| Substrate Smiles | CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)CO |
| Substrate Structure |
Product Information:
| Product Name | Betulinate |
| Product Chemical Formula | C30H47O3- |
| Product PubChem CID | 40473200 |
| Product Smiles | CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C(=O)[O-] |
| Product Structure |
References:
| Title: | Molecular characterization of the pentacyclic triterpenoid biosynthetic pathway in Catharanthus roseus. |
| PMID: | 22837051 |
| Journal: | Planta |
| Year: | 2012/11/1 |