Detail Information
P450 Protein:
| P450 Symbol | CYP716A46 |
| Protein Name | Beta-amyrin 28-monooxygenase |
| Uniprot ID | K4CEE8 |
| EC Number | 1.14.14.126 |
| Gene ID | 101252702 |
| Species | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
| Txid | 4081 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H48O2 → C30H48O3 |
| Reaction Type | Oxidation |
| Chemical Bond | Aldehyde |
CYP716A46
Substrate Information:
| Substrate Name | Oleanolic Aldehyde |
| Substrate Chemical Formula | C30H48O2 |
| Substrate PubChem CID | 10321055 |
| Substrate Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C=O)C)C)(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | OLEANOLIC ACID |
| Product Chemical Formula | C30H48O3 |
| Product PubChem CID | 10494 |
| Product Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O |
| Product Structure |
References:
| Title: | Functional Characterization of CYP716 Family P450 Enzymes in Triterpenoid Biosynthesis in Tomato. |
| PMID: | 28194155 |
| Journal: | Frontiers in plant science |
| Year: | 2017/1/1 |