Detail Information

P450 Protein:

P450 SymbolCYP714E19
Protein Name/
Uniprot ID/
SpeciesCentella asiatica
Txid 48106
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location/
Protein Sequence GO
RemarksGenBank:KT004520.1

Reaction Scheme:

Chemical Conversion C30H48O3 → C30H48O4
Reaction TypeOxidation
Chemical BondCH3

Oleanolic Acid

CYP714E19

Hederagenin

Substrate Information:

Substrate Name Oleanolic Acid
Substrate Chemical FormulaC30H48O3
Substrate PubChem CID10494
Substrate SmilesC[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)C)O
Substrate Structure

Product Information:

Product Name Hederagenin
Product Chemical FormulaC30H48O4
Product PubChem CID73299
Product SmilesC[C@]12CC[C@@H]([C@@]([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)C)C)(C)CO)O
Product Structure

References:

Title: A Novel Multifunctional C-23 Oxidase, CYP714E19, is Involved in Asiaticoside Biosynthesis.
PMID: 29579306
Journal: Plant & cell physiology
Year: 2018/6/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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