Detail Information

P450 Protein:

P450 SymbolCYP714E19
Protein Name/
Uniprot ID/
SpeciesCentella asiatica
Txid 48106
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location/
Protein Sequence GO
RemarksGenBank:KT004520.1

Reaction Scheme:

Chemical Conversion C30H50O2 → C30H50O3
Reaction TypeOxidation
Chemical BondCH3

Uvaol

CYP714E19

23-Hydroxyuvaol

Substrate Information:

Substrate Name Uvaol
Substrate Chemical FormulaC30H50O2
Substrate PubChem CID92802
Substrate SmilesC[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)O)C)C)[C@@H]2[C@H]1C)C)CO
Substrate Structure

Product Information:

Product Name 23-Hydroxyuvaol
Product Chemical FormulaC30H50O3
Product SmilesC(C)(CO)1[C@@H](O)CC[C@@](C)2C3CC=C4C5[C@@H](C)[C@@H](C)CC[C@]5(CO)CC[C@]4(C)[C@]3(C)CCC12
Product Structure

References:

Title: A Novel Multifunctional C-23 Oxidase, CYP714E19, is Involved in Asiaticoside Biosynthesis.
PMID: 29579306
Journal: Plant & cell physiology
Year: 2018/6/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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