Detail Information
P450 Protein:
| P450 Symbol | CYP714E19 |
| Protein Name | / |
| Uniprot ID | / |
| Species | Centella asiatica |
| Txid | 48106 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein |
| Protein Sequence | GO |
| Remarks | GenBank:KT004520.1 |
Reaction Scheme:
| Chemical Conversion | C30H46O4 → C30H46O5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP714E19
Substrate Information:
| Substrate Name | 3-Hydroxy-23-Oxours-12-En-28-Oic Acid |
| Substrate Chemical Formula | C30H46O4 |
| Substrate Smiles | [C@@H](C)1[C@@H](C)CC[C@@](C(O)=O)2CC[C@](C)3[C@@](C)4CCC5C(C)(C=O)[C@@H](O)CC[C@]5(C)C4CC=C3C12 |
| Substrate Structure |
Product Information:
| Product Name | 3-Hydroxyurs-12-Ene-23,28-Dioic Acid |
| Product Chemical Formula | C30H46O5 |
| Product Smiles | C(C)(C(=O)O)1[C@@H](O)CC[C@@](C)2C3CC=C4C5[C@@H](C)[C@@H](C)CC[C@]5(C(O)=O)CC[C@]4(C)[C@]3(C)CCC12 |
| Product Structure |
References:
| Title: | A Novel Multifunctional C-23 Oxidase, CYP714E19, is Involved in Asiaticoside Biosynthesis. |
| PMID: | 29579306 |
| Journal: | Plant & cell physiology |
| Year: | 2018/6/1 |