Detail Information
P450 Protein:
| P450 Symbol | CYP76B1 |
| Protein Name | 7-ethoxycoumarin O-deethylase |
| Uniprot ID | O23976 |
| EC Number | 1.14.-.- |
| Species | Helianthus tuberosus (Jerusalem artichoke) (Helianthus tomentosus) |
| Txid | 4233 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C11H10O3 → C9H6O3 |
| Reaction Type | Decomposition |
| Chemical Bond | C-O |
CYP76B1
Substrate Information:
| Substrate Name | 7-Ethoxycoumarin |
| Substrate Chemical Formula | C11H10O3 |
| Substrate PubChem CID | 35703 |
| Substrate Smiles | CCOC1=CC2=C(C=C1)C=CC(=O)O2 |
| Substrate Structure |
Product Information:
| Product Name | Umbelliferone |
| Product Chemical Formula | C9H6O3 |
| Product PubChem CID | 5281426 |
| Product Smiles | C1=CC(=CC2=C1C=CC(=O)O2)O |
| Product Structure |
References:
| Title: | The chemically inducible plant cytochrome P450 CYP76B1 actively metabolizes phenylureas and other xenobiotics. |
| PMID: | 9808750 |
| Journal: | Plant physiology |
| Year: | 1998/11/1 |