Detail Information

P450 Protein:

P450 SymbolCYP106A2
Protein NameCytochrome P450(MEG)
Uniprot IDQ06069
SpeciesPriestia megaterium ATCC 13368
Txid 1404
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C21H30O4 → C21H30O5
Reaction TypeOxidation
Chemical BondCH2

11-Deoxycortisol

CYP106A2

15Beta-Hydroxy-11-Deoxycortisol

Substrate Information:

Substrate Name 11-Deoxycortisol
Substrate Chemical FormulaC21H30O4
Substrate PubChem CID440707
Substrate SmilesC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C
Substrate Structure

Product Information:

Product Name 15Beta-Hydroxy-11-Deoxycortisol
Product Chemical FormulaC21H30O5
Product PubChem CID14411522
Product SmilesC[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2CC[C@]4([C@H]3[C@@H](C[C@@]4(C(=O)CO)O)O)C
Product Structure

References:

Title: Comparison of CYP106A1 and CYP106A2 from Bacillus megaterium?-?identification of a novel 11-oxidase activity.
PMID: 25904128
Journal: Applied microbiology and biotechnology
Year: 2015/10/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics