Detail Information

P450 Protein:

P450 SymbolCYP2J2
Protein NameCytochrome P450 2J2
Uniprot IDP51589
EC Number1.14.14.-; 1.14.14.73; 1.14.14.74; 5.4.4.7
Gene ID 1573
SpeciesHomo sapiens (Human)
Txid 9606
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular LocationMembrane; Single-pass membrane protein
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C20H31O4- → C20H31O4-
Reaction TypeOxidation
Chemical BondO-O
RheaID 53400

(15S)-Hydroperoxy-(5Z,8Z,11Z,13E)-Eicosatetraenoate

CYP2J2

(13S)-Hydroxy-(14S,15S)-Epoxy-(5Z,8Z,11Z)-Eicosatrienoate

Substrate Information:

Substrate Name (15S)-Hydroperoxy-(5Z,8Z,11Z,13E)-Eicosatetraenoate
Substrate Chemical FormulaC20H31O4-
Substrate PubChem CID21158477
Substrate SmilesCCCCC[C@@H](/C=C/C=CC/C=CC/C=CCCCC(=O)[O-])OO
Substrate Structure

Product Information:

Product Name (13S)-Hydroxy-(14S,15S)-Epoxy-(5Z,8Z,11Z)-Eicosatrienoate
Product Chemical FormulaC20H31O4-
Product PubChem CID129626618
Product SmilesCCCCC[C@H]1[C@@H](O1)[C@H](/C=CC/C=CC/C=CCCCC(=O)[O-])O
Product Structure

References:

Title: Identification of 13-hydroxy-14,15-epoxyeicosatrienoic acid as an acid-stable endothelium-derived hyperpolarizing factor in rabbit arteries.
PMID: 19737933
Journal: The Journal of biological chemistry
Year: 2009/11/6

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics