Detail Information
P450 Protein:
| P450 Symbol | CYP124A |
| Protein Name | Methyl-branched lipid omega-hydroxylase |
| Uniprot ID | P9WPP3 |
| EC Number | 1.14.15.14; 1.14.15.28 |
| Gene ID | 45426248 |
| Species | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) |
| Txid | 83332 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C15H26O → C15H26O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP124A
Substrate Information:
| Substrate Name | Farnesol |
| Substrate Chemical Formula | C15H26O |
| Substrate PubChem CID | 445070 |
| Substrate Smiles | CC(=CCC/C(=C/CC/C(=C/CO)/C)/C)C |
| Substrate Structure |
Product Information:
| Product Name | (2E,6E,10E)-2,6,10-trimethyldodeca-2,6,10-triene-1,12-diol |
| Product Chemical Formula | C15H26O2 |
| Product Smiles | C(O)/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CO |
| Product Structure |
References:
| Title: | Biochemical and structural characterization of CYP124: a methyl-branched lipid omega-hydroxylase from Mycobacterium tuberculosis. |
| PMID: | 19933331 |
| Journal: | Proceedings of the National Academy of Sciences of the United States of America |
| Year: | 2009/12/8 |