Detail Information

P450 Protein:

P450 SymbolCYP734A7
Protein NameCastasterone 26-hydroxylase
Uniprot IDQ0X087
Gene ID 100736544
SpeciesSolanum lycopersicum (Tomato) (Lycopersicon esculentum)
Txid 4081
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular LocationMicrosome membrane; Peripheral membrane protein Endoplasmic reticulum membrane; Peripheral membrane protein
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C27H46O5 → C27H46O6
Reaction TypeOxidation
Chemical BondCH3

28-Norcastasterone

CYP734A7

26-Hydroxynorcastasterone

Substrate Information:

Substrate Name 28-Norcastasterone
Substrate Chemical FormulaC27H46O5
Substrate PubChem CID13982110
Substrate SmilesC[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@H]4[C@@]3(C[C@H]([C@H](C4)O)O)C)C)[C@H]([C@@H](CC(C)C)O)O
Substrate Structure

Product Information:

Product Name 26-Hydroxynorcastasterone
Product Chemical FormulaC27H46O6
Product Smiles[C@]12(C(=O)CC3C4CCC([C@@H]([C@@H](O)[C@H](O)CC(C)CO)C)[C@@]4(C)CCC3[C@@]1(C)C[C@@H](O)[C@@H](O)C2)[H]
Product Structure

References:

Title: Tomato cytochrome P450 CYP734A7 functions in brassinosteroid catabolism.
PMID: 16872648
Journal: Phytochemistry
Year: 2006/9/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
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