Detail Information
P450 Protein:
| P450 Symbol | CYP80F1 |
| Protein Name | Littorine mutase/monooxygenase |
| Uniprot ID | Q1A1B0 |
| Species | Hyoscyamus niger (Black henbane) |
| Txid | 4079 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C17H23NO3 → C17H22NO3+ |
| Reaction Type | Oxidation |
| Chemical Bond | CH-OH;-N- |
CYP80F1
Substrate Information:
| Substrate Name | (R)-Littorine |
| Substrate Chemical Formula | C17H23NO3 |
| Substrate PubChem CID | 12311316 |
| Substrate Smiles | CN1[C@@H]2CC[C@H]1CC(C2)OC(=O)[C@@H](CC3=CC=CC=C3)O |
| Substrate Structure |
Product Information:
| Product Name | Hyoscyamine Aldehyde |
| Product Chemical Formula | C17H22NO3+ |
| Product PubChem CID | 145865034 |
| Product Smiles | C[NH+]1[C@@H]2CC[C@H]1CC(C2)OC(=O)C(C=O)C3=CC=CC=C3 |
| Product Structure |
References:
| Title: | Functional genomic analysis of alkaloid biosynthesis in Hyoscyamus niger reveals a cytochrome P450 involved in littorine rearrangement. |
| PMID: | 16720272 |
| Journal: | Chemistry & biology |
| Year: | 2006/5/1 |