Detail Information
P450 Protein:
| P450 Symbol | CYP716A12 |
| Protein Name | Beta-amyrin 28-monooxygenase |
| Uniprot ID | Q2MJ20 |
| EC Number | 1.14.14.126 |
| Gene ID | 25502252 |
| Species | Medicago truncatula (Barrel medic) (Medicago tribuloides) |
| Txid | 3880 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H50O2 → C30H48O2 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2-OH |
CYP716A12
Substrate Information:
| Substrate Name | Erythrodiol |
| Substrate Chemical Formula | C30H50O2 |
| Substrate PubChem CID | 101761 |
| Substrate Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)CO)C)C)(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | Oleanolic Aldehyde |
| Product Chemical Formula | C30H48O2 |
| Product PubChem CID | 10321055 |
| Product Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(CC[C@@]5([C@H]4CC(CC5)(C)C)C=O)C)C)(C)C)O |
| Product Structure |
References:
| Title: | Medicago truncatula CYP716A12 is a multifunctional oxidase involved in the biosynthesis of hemolytic saponins. |
| PMID: | 21821776 |
| Journal: | The Plant cell |
| Year: | 2011/8/1 |
| Title: | CYP716A subfamily members are multifunctional oxidases in triterpenoid biosynthesis. |
| PMID: | 22039103 |
| Journal: | Plant & cell physiology |
| Year: | 2011/12/1 |