Detail Information
P450 Protein:
| P450 Symbol | CYP72A67 |
| Protein Name | Cytochrome P450 716A67 |
| Uniprot ID | Q2MJ21 |
| EC Number | 1.14.13.- |
| Gene ID | 25486186 |
| Species | Medicago truncatula (Barrel medic) (Medicago tribuloides) |
| Txid | 3880 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C30H48O4 → C30H48O5 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP72A67
Substrate Information:
| Substrate Name | Echinocystic Acid |
| Substrate Chemical Formula | C30H48O4 |
| Substrate PubChem CID | 73309 |
| Substrate Smiles | C[C@]12CC[C@@H](C([C@@H]1CC[C@@]3([C@@H]2CC=C4[C@]3(C[C@H]([C@@]5([C@H]4CC(CC5)(C)C)C(=O)O)O)C)C)(C)C)O |
| Substrate Structure |
Product Information:
| Product Name | 2Beta-Hydroxyechnocystic Acid |
| Product Chemical Formula | C30H48O5 |
| Product PubChem CID | 20055767 |
| Product Smiles | C[C@@]12[C@H]3CC=C4[C@@H]5CC(C)(C)CC[C@]5(C(O)=O)[C@H](O)C[C@]4([C@]3(C)CC[C@H]1C(C)(C)[C@@H](O)[C@@H](O)C2)C |
| Product Structure |
References:
| Title: | CYP72A67 Catalyzes a Key Oxidative Step in Medicago truncatula Hemolytic Saponin Biosynthesis. |
| PMID: | 26079384 |
| Journal: | Molecular plant |
| Year: | 2015/10/5 |