Detail Information
P450 Protein:
| P450 Symbol | SlCYP85A1 |
| Protein Name | Cytochrome P450 85A1 |
| Uniprot ID | Q43147 |
| EC Number | 1.14.14.- |
| Gene ID | 100037489 |
| Species | Solanum lycopersicum (Tomato) (Lycopersicon esculentum) |
| Txid | 4081 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Membrane; Single-pass membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C28H50O3 → C28H48O4 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
SlCYP85A1
Substrate Information:
| Substrate Name | 6-Deoxoteasterone |
| Substrate Chemical Formula | C28H50O3 |
| Substrate PubChem CID | 11144580 |
| Substrate Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C)[C@H]([C@@H]([C@@H](C)C(C)C)O)O |
| Substrate Structure |
Product Information:
| Product Name | Teasterone |
| Product Chemical Formula | C28H48O4 |
| Product PubChem CID | 13475125 |
| Product Smiles | C[C@@H]([C@H]1CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC(=O)[C@@H]4[C@@]3(CC[C@@H](C4)O)C)C)[C@H]([C@@H]([C@@H](C)C(C)C)O)O |
| Product Structure |
References:
| Title: | Brassinosteroid-6-oxidases from Arabidopsis and tomato catalyze multiple C-6 oxidations in brassinosteroid biosynthesis. |
| PMID: | 11402205 |
| Journal: | Plant physiology |
| Year: | 2001/6/1 |
| Title: | The tomato DWARF enzyme catalyses C-6 oxidation in brassinosteroid biosynthesis. |
| PMID: | 9990098 |
| Journal: | Proceedings of the National Academy of Sciences of the United States of America |
| Year: | 1999/2/16 |