Detail Information
P450 Protein:
| P450 Symbol | CYP63A2 |
| Protein Name | Cytochrome P450 monooxygenase pc-3 |
| Uniprot ID | Q56VS2 |
| Species | Phanerodontia chrysosporium (White-rot fungus) (Sporotrichum pruinosum) |
| Txid | 2822231 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C16H8 → C20H12O |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
CYP63A2
Substrate Information:
| Substrate Name | Benzo(Alpha)Pyrene |
| Substrate Chemical Formula | C16H8 |
| Substrate PubChem CID | 90044747 |
| Substrate Smiles | C1=CC2=C3C(=C1)C4=C5C=CC(=C4)C3=C5C=C2 |
| Substrate Structure |
Product Information:
| Product Name | Benzo(Alpha)Pyrene-3-Ol |
| Product Chemical Formula | C20H12O |
| Product PubChem CID | 25890 |
| Product Smiles | C1C=C2C3C=CC4=CC=C(O)C5=C4C=3C(C=C5)=CC2=CC=1 |
| Product Structure |
References:
| Title: | CYP63A2, a catalytically versatile fungal P450 monooxygenase capable of oxidizing higher-molecular-weight polycyclic aromatic hydrocarbons, alkylphenols, and alkanes. |
| PMID: | 23416995 |
| Journal: | Applied and environmental microbiology |
| Year: | 2013/4/1 |