P450 Protein:
| P450 Symbol | MycG |
| Protein Name | Mycinamicin IV hydroxylase/epoxidase |
| Uniprot ID | Q59523 |
| EC Number | 1.14.-.- |
| Species | Micromonospora griseorubida |
| Txid | 28040 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C37H61NO11 → C37H61NO12 |
| Reaction Type | Oxidation |
| Chemical Bond | CH-CH |
MycG
Substrate Information:
| Substrate Name | Mycinamicin Iv |
| Substrate Chemical Formula | C37H61NO11 |
| Substrate PubChem CID | 6447311 |
| Substrate Smiles | CC[C@@H]1[C@H](/C=C/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H](/C=C/C(=O)O1)C)O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)C)C)CO[C@H]3[C@@H]([C@@H]([C@@H]([C@H](O3)C)O)OC)OC |
| Substrate Structure |
Product Information:
| Product Name | Mycinamicin I |
| Product Chemical Formula | C37H61NO12 |
| Product PubChem CID | 6447308 |
| Product Smiles | CC[C@@H]1[C@H](C2C(O2)/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H](/C=C/C(=O)O1)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)C)C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC |
| Product Structure |
References:
| Title: | Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics. |
| PMID: | 18804032 |
| Journal: | Chemistry & biology |
| Year: | 2008/9/22 |