Detail Information

P450 Protein:

P450 SymbolMycG
Protein NameMycinamicin IV hydroxylase/epoxidase
Uniprot IDQ59523
EC Number1.14.-.-
SpeciesMicromonospora griseorubida
Txid 28040
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C37H61NO11 → C37H61NO12
Reaction TypeOxidation
Chemical BondCH-CH

Mycinamicin Iv

MycG

Mycinamicin I

Substrate Information:

Substrate Name Mycinamicin Iv
Substrate Chemical FormulaC37H61NO11
Substrate PubChem CID6447311
Substrate SmilesCC[C@@H]1[C@H](/C=C/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H](/C=C/C(=O)O1)C)O[C@H]2[C@@H]([C@H](C[C@H](O2)C)N(C)C)O)C)C)CO[C@H]3[C@@H]([C@@H]([C@@H]([C@H](O3)C)O)OC)OC
Substrate Structure

Product Information:

Product Name Mycinamicin I
Product Chemical FormulaC37H61NO12
Product PubChem CID6447308
Product SmilesCC[C@@H]1[C@H](C2C(O2)/C=C/C(=O)[C@@H](C[C@@H]([C@@H]([C@H](/C=C/C(=O)O1)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)C)C)CO[C@H]4[C@@H]([C@@H]([C@@H]([C@H](O4)C)O)OC)OC
Product Structure

References:

Title: Functional analysis of MycCI and MycG, cytochrome P450 enzymes involved in biosynthesis of mycinamicin macrolide antibiotics.
PMID: 18804032
Journal: Chemistry & biology
Year: 2008/9/22

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics