Detail Information
P450 Protein:
| P450 Symbol | CYP4A22 |
| Protein Name | Cytochrome P450 4A22 |
| Uniprot ID | Q5TCH4 |
| EC Number | 1.14.14.80 |
| Gene ID | 284541 |
| Species | Homo sapiens (Human) |
| Txid | 9606 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein Microsome membrane; Peripheral membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C2H3O2R- → C2H3O3R- |
| Reaction Type | Oxidation |
| Chemical Bond | CH3 |
| RheaID | 56748 |
CYP4A22
Substrate Information:
| Substrate Name | An Omega-Methyl-Long-Chain Fatty Acid |
| Substrate Chemical Formula | C2H3O2R- |
| Substrate Smiles | C*C([O-])=O |
| Substrate Structure |
Product Information:
| Product Name | An Omega-Hydroxy-Long-Chain Fatty Acid |
| Product Chemical Formula | C2H3O3R- |
| Product PubChem SID | 85340664 |
| Product Smiles | OC[*]C([O-])=O |
| Product Structure |
References:
| Title: | Human fatty acid omega-hydroxylase, CYP4A11: determination of complete genomic sequence and characterization of purified recombinant protein. |
| PMID: | 10860550 |
| Journal: | Archives of biochemistry and biophysics |
| Year: | 2000/6/15 |