Detail Information
P450 Protein:
| P450 Symbol | CYP714A2 |
| Protein Name | Cytochrome P450 714A2 |
| Uniprot ID | Q6NKZ8 |
| EC Number | 1.14.-.- |
| Gene ID | 832559 |
| Species | Arabidopsis thaliana (Mouse-ear cress) |
| Txid | 3702 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Single-pass type III membrane protein |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C20H28O4 → C20H28O6 |
| Reaction Type | Oxidation |
| Chemical Bond | CH2 |
CYP714A2
Substrate Information:
| Substrate Name | Gibberellin A12 |
| Substrate Chemical Formula | C20H28O4 |
| Substrate PubChem CID | 443450 |
| Substrate Smiles | C[C@@]12CCC[C@@]([C@H]1[C@@H]([C@]34[C@H]2CC[C@H](C3)C(=C)C4)C(=O)O)(C)C(=O)O |
| Substrate Structure |
Product Information:
| Product Name | 16-Carboxy GA12 |
| Product Chemical Formula | C20H28O6 |
| Product Smiles | C[C@]12[C@@H]3CC[C@H]4C(C[C@@]3(C4)[C@@H](C(O)=O)[C@@H]1[C@@](C(O)=O)(C)CCC2)C(O)=O |
| Product Structure |
References:
| Title: | Functional analysis of Arabidopsis CYP714A1 and CYP714A2 reveals that they are distinct gibberellin modification enzymes. |
| PMID: | 24009336 |
| Journal: | Plant & cell physiology |
| Year: | 2013/11/1 |