Detail Information
P450 Protein:
| P450 Symbol | CYP98A6 |
| Protein Name | Cytochrome P-450 |
| Uniprot ID | Q8GSQ6 |
| Species | Lithospermum erythrorhizon (Purple gromwell) (Lithospermum officinale var. erythrorhizon) |
| Txid | 34254 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | / |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C18H16O7 → C18H16O8 |
| Reaction Type | Oxidation |
| Chemical Bond | CH |
CYP98A6
Substrate Information:
| Substrate Name | 2-O-(4-Coumaroyl)-3-(3,4-Dihydroxyphenyl)Lactic Acid |
| Substrate Chemical Formula | C18H16O7 |
| Substrate Smiles | C1C=C(/C=C/C(=O)OC(C(O)=O)CC2=CC=C(O)C(O)=C2)C=CC=1O |
| Substrate Structure |
Product Information:
| Product Name | Rosmarinic Acid |
| Product Chemical Formula | C18H16O8 |
| Product PubChem CID | 5281792 |
| Product Smiles | C1=CC(=C(C=C1C[C@H](C(=O)O)OC(=O)/C=C/C2=CC(=C(C=C2)O)O)O)O |
| Product Structure |
References:
| Title: | CYP98A6 from Lithospermum erythrorhizon encodes 4-coumaroyl-4'-hydroxyphenyllactic acid 3-hydroxylase involved in rosmarinic acid biosynthesis. |
| PMID: | 11943155 |
| Journal: | FEBS letters |
| Year: | 2002/3/13 |