Detail Information

P450 Protein:

P450 SymbolNtCYP51
Protein NameObtusifoliol-14-demethylase
Uniprot IDQ8GZV0
Gene ID 107764727
SpeciesNicotiana tabacum (Common tobacco)
Txid 4097
P450 Protein Structure
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
Powered by PDBe Molstar & AlphaFold
Subcellular Location/
Protein Sequence GO

Reaction Scheme:

Chemical Conversion C30H50O → C29H46O
Reaction TypeDecomposition
Chemical BondCH3

Obtusifoliol

NtCYP51

4Alpha-Methyl-Ergost-8,14,24(24′)-Trien-3Beta-Ol

Substrate Information:

Substrate Name Obtusifoliol
Substrate Chemical FormulaC30H50O
Substrate PubChem CID65252
Substrate SmilesC[C@H]1[C@@H]2CCC3=C([C@]2(CC[C@@H]1O)C)CC[C@]4([C@]3(CC[C@@H]4[C@H](C)CCC(=C)C(C)C)C)C
Substrate Structure

Product Information:

Product Name 4Alpha-Methyl-Ergost-8,14,24(24′)-Trien-3Beta-Ol
Product Chemical FormulaC29H46O
Product PubChem CID60123239
Product SmilesC1C[C@@](C)2C3CC[C@@](C)4C([C@@H](CCC(=C)C(C)C)C)CC=C4C=3CCC2[C@H](C)[C@H]1O
Product Structure

References:

Title: Virus-induced silencing of sterol biosynthetic genes: identification of a Nicotiana tabacum L. obtusifoliol-14alpha-demethylase (CYP51) by genetic manipulation of the sterol biosynthetic pathway in Nicotiana benthamiana L.
PMID: 12810855
Journal: Journal of experimental botany
Year: 2003/7/1

Contact zhy1001@alu.uestc.edu.cn or yangzhang@cdutcm.edu.cn
© Department of Bioinformatics