Detail Information
P450 Protein:
| P450 Symbol | CYP74A |
| Protein Name | Allene oxide synthase, chloroplastic |
| Uniprot ID | Q96242 |
| EC Number | 4.2.1.92 |
| Gene ID | 834273 |
| Species | Arabidopsis thaliana (Mouse-ear cress) |
| Txid | 3702 |
| P450 Protein Structure |
Model Confidence (pLDDT)
Very high (>90)
High (90 > 70)
Low (70 > 50)
Very low (<50)
|
| Subcellular Location | Endoplasmic reticulum membrane; Peripheral membrane protein Mitochondrion inner membrane; Peripheral membrane protein Microsome membrane; Peripheral membrane protein Cytoplasm |
| Protein Sequence | GO |
Reaction Scheme:
| Chemical Conversion | C18H31O4- → C18H29O3- + H2O |
| Reaction Type | Reduction |
| Chemical Bond | O-O |
| RheaID | 84075 |
CYP74A
+
Substrate Information:
| Substrate Name | (13S)-hydroperoxy-(9Z,11E)-octadecadienoate |
| Substrate Chemical Formula | C18H31O4- |
| Substrate PubChem CID | 21158461 |
| Substrate Smiles | CCCCC[C@@H](/C=C/C=CCCCCCCCC(=O)[O-])OO |
| Substrate Structure |
Product Information:
| Product Name | (9Z,13S)-12,13-epoxyoctadeca-9,11-dienoate |
| Product Chemical Formula | C18H29O3- |
| Product PubChem CID | 46878374 |
| Product Smiles | CCCCC[C@H]1/C(=C/C=CCCCCCCCC(=O)[O-])/O1 |
| Product Structure |
| Product Name | H2O |
| Product Chemical Formula | H2O |
| Product PubChem CID | 962 |
| Product CAS Number | 7732-18-5 |
| Product Smiles | O |
| Product Structure |
References:
| Title: | Cloning, molecular and functional characterization of Arabidopsis thaliana allene oxide synthase (CYP 74), the first enzyme of the octadecanoid pathway to jasmonates. |
| PMID: | 8756596 |
| Journal: | Plant molecular biology |
| Year: | 1996/5/1 |